Sam Warburton will miss Wales’ game against South Africa on Saturday after suffering an injury in training.
His place in the back-row is taken by Dan Lydiate, with Justin Tipuric restored to the open-side and Taulupe Faletau on the bench after injury.
Leigh Halfpenny moves to full-back after playing on the wing in the 33-30 win over Japan.
Scott Williams is preferred at centre to Jamie Roberts in a side showing one change from the win over Argentina.
Loose-head Gethin Jenkins is captain after recovering from a shoulder injury.
Warburton missed the opening game of the autumn series against Australia as he recovered from shoulder and neck injuries, but played in the wins over the Pumas and Japan.
Faletau appears in the squad for the first time this autumn having played an hour for Bath against Bristol following a knee injury suffered in September.
Halfpenny’s return to the number 15 shirt sees Liam Williams move to the wing.
Dan Biggar returns at fly-half, with Sam Davies – whose last-minute drop goal clinched the win against Japan – getting the nod ahead of Gareth Anscombe on the bench.
“We were pleased with the win against Argentina so have gone with virtually the same team for South Africa,” said head coach Rob Howley.
“Sam [Warburton] picked up a bit of a stinger injury on Tuesday and isn’t quite ready so Dan comes in.
“It’s good to have Taulupe back in the squad, he will add a good impact from the bench.
“There is the tinge of disappointment in terms of performance against Japan and we want to put that right.”
Wales: Halfpenny; North, J Davies, S Williams, Liam Williams; Biggar, G Davies; Jenkins (capt), Owens, Francis, Charteris, Wyn Jones, Lydiate, Moriarty, Tipuric.
Replacements: Baldwin, Smith, Lee, Hill, Faletau, Lloyd Williams, S Davies, Roberts.
Article source: http://www.bbc.co.uk/sport/rugby-union/38085271