Wasps centre Elliot Daly and Northampton flanker Tom Wood will start for England in Saturday’s Test match against South Africa at Twickenham.
Head coach Eddie Jones has confirmed Daly, 24, will make his first international start, replacing Bath’s Jonathan Joseph at outside centre.
Wood, 30, will line up at open-side flanker for his first England appearance in more than a year.
Debutants Kyle Sinckler, Nathan Hughes and Ben Te’o are named on the bench.
Jonny May returns on the wing, while second row Courtney Lawes wins his 50th cap.
Daly, who has won five caps as a replacement, will form a new midfield partnership with Saracens’ Owen Farrell.
“We’ve picked a matchday 23 with a blend of experience and youth,” said Jones.
The Australian is without injured back-row contenders James Haskell, Maro Itoje, Jack Clifford, Sam Jones and Mike Williams, while winger Anthony Watson has a broken jaw.
“It’s a fantastic opportunity to show how much depth we have in English rugby,” added Jones.
“With a few influential players not available for selection, this is a great opportunity for some of the new faces to put both feet forward and we’re backing them to do the job for us.”
With Daly starting, Joseph – who had been struggling with a groin injury – drops to the bench.
Former England captain Mike Tindall told BBC Radio 5 live Daly’s selection was not a big shock.
“I was lucky to play with him at Barbarians – he’s just got a fantastic skill-set and the ability to beat people,” said the World Cup winner.
“Elliot is a little bit more classy. He will beat you by subtlety rather than when Jonathan Joseph will stand up and go around you.”
Back row Josh Beaumont and hooker Tommy Taylor are the two players to drop out of Jones’ initial 25-man squad, but will travel as reserves.
South Africa are experiencing their worst run of results for a decade, having lost five of their past nine matches, including a record home defeat by New Zealand.
Former Springbok Hennie le Roux believes the visitors are “ripe for the taking”.
Team: Mike Brown (Harlequins); Marland Yarde (Harlequins), Elliot Daly (Wasps), Owen Farrell (Saracens), Jonny May (Gloucester Rugby); George Ford (Bath Rugby), Ben Youngs (Leicester Tigers); Mako Vunipola (Saracens), Dylan Hartley (Northampton Saints), Dan Cole (Leicester Tigers); Joe Launchbury (Wasps), Courtney Lawes (Northampton Saints); Chris Robshaw (Harlequins), Tom Wood (Northampton Saints), Billy Vunipola (Saracens).
Replacements: Jamie George (Saracens), Joe Marler (Harlequins), Kyle Sinckler (Harlequins), Dave Attwood (Bath Rugby), Nathan Hughes (Wasps), Danny Care (Harlequins), Ben Te’o (Worcester Warriors), Jonathan Joseph (Bath Rugby).
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Article source: http://www.bbc.co.uk/sport/rugby-union/37931642